Co-localization of Cell Lineage Markers and the Tomato SignalYan Jing 1, Robert J. Hinton 1, Kevin S. Chan 1, Jian Q. Feng 1
1Department of Biomedical Sciences, Texas A&M University College of Dentistry
We developed two sets of tracing combinations in Rosa26tdtomato (ubiquitously expressed in all cells)/Cre (specifically expressed in chondrocytes) mice: one with 2.3Col1a1-GFP (specific to osteoblasts) and one with immunofluorescence (specific to bone cells). The data demonstrate the direct transformation of chondrocytes into bone cells.
